منابع مشابه
Dmd062596 510..522
Clopidogrel is a prodrug that needs to be converted to its active metabolite (clopi-H4) in two sequential cytochrome P450 (P450)dependent steps. In the present study, a dynamic physiologically based pharmacokinetic (PBPK) model was developed in Simcyp for clopidogrel and clopi-H4 using a specific sequential metabolite module in four populations with phenotypically different CYP2C19 activity (po...
متن کاملN414_29c 522..525
The X-ray source known as GRS1915+105 belongs to a group dubbed `microquasars'. These objects are binary systems which sporadically eject matter at speeds that appear superluminal, as is the case for some quasars. GRS1915+105 is also one of only two known binary sources thought to contain a maximally spinning black hole. Determining the basic parameters of GRS195+105, such as the masses of the ...
متن کاملCOS 522: Assumed Knowledge
This document includes some mathematical notions I will assume. Most of these are taught in a discrete math class, and in any case are not complicated and easy to pick up. You can read it at your own pace — it will take a few weeks until we’ll get to use all of this stuff. You do not have to do the exercises, and in any case don’t need to submit them. If you feel you’d like more clarifications ...
متن کاملDev115931 522..532
Cortical lamination is crucial for the assembly of cerebellar circuitry. In this process, granule neurons (GNs) migrate along Bergmann glia (BG), which are specialized astroglial cells, from the external granule layer to the internal granule layer. However, the molecular mechanisms underlying BG development are not well understood. Here, we show that GFAP::Cre;Erbb3 mice, which lack Erbb3 in bo...
متن کاملC2nr33212d 518..522
Shape oen has a decisive inuence over the properties and applications of monodisperse nanoparticles. In addition, size is another important factor controlling the properties of the nanomaterials owing to various connement effects. Therefore, the synthesis of diverse, high-quality nanoparticles with tunable shapes and sizes has become a challenging issue and drawn considerable attention. Morp...
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ژورنال
عنوان ژورنال: Astronomische Nachrichten
سال: 1906
ISSN: 0004-6337,1521-3994
DOI: 10.1002/asna.19061711506